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Urinary mercury excretion in chloralkali workers after the cessation of exposure.
- Source :
-
Scandinavian journal of work, environment & health [Scand J Work Environ Health] 1993 Oct; Vol. 19 (5), pp. 334-41. - Publication Year :
- 1993
-
Abstract
- Seventeen former chloralkali workers were followed through the regular determination of urinary mercury for nearly two years after the cessation of exposure to mercury vapor in a study of the time course of urinary mercury elimination. Their duration of exposure ranged from 3 d to 35.5 years. A one-compartment model for urinary mercury elimination was applied. The urinary mercury concentration declined at a rate indicating a half-time of 91 d. When corrected for an individual base-line level of urinary mercury resulting from sources of mercury intake not related to work, the half-time was 72.4 [95% confidence interval (95% CI) 63.2-81.7] d, with a mean elimination rate constant of 0.011 (95% CI 0.008-0.013).d-1. The day-to-day variability of the urinary mercury concentration averaged 22%, expressed as the coefficient of variation between urine samples delivered on three consecutive days.
- Subjects :
- Adolescent
Adult
Air Pollutants, Occupational adverse effects
Female
Follow-Up Studies
Humans
Male
Mercury Poisoning urine
Metabolic Clearance Rate physiology
Middle Aged
Occupational Diseases urine
Air Pollutants, Occupational pharmacokinetics
Alkalies
Mercury pharmacokinetics
Mercury Poisoning diagnosis
Occupational Diseases chemically induced
Occupational Exposure adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 0355-3140
- Volume :
- 19
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Scandinavian journal of work, environment & health
- Publication Type :
- Academic Journal
- Accession number :
- 8296182
- Full Text :
- https://doi.org/10.5271/sjweh.1466