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Critique of the toxicology and carcinogenesis studies of iodinated glycerol in F344/N rats and B6C3F1 mice.
- Source :
-
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 1993 Oct; Vol. 18 (2), pp. 169-80. - Publication Year :
- 1993
-
Abstract
- Carter-Wallace conducted a detailed audit and evaluation of the data available from the carcinogenicity studies with iodinated glycerol conducted in the B6C3F1 mouse and the F344/N rat by the National Toxicology Program (NTP). We conclude that there is no evidence of carcinogenicity of the compound in either the B6C3F1 mouse or the F344/N rat.
- Subjects :
- Adenoma chemically induced
Adenoma pathology
Animals
Female
Glycerol toxicity
Leukemia, Monocytic, Acute chemically induced
Leukemia, Monocytic, Acute pathology
Male
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Murine hepatitis virus
Parainfluenza Virus 1, Human
Pituitary Neoplasms chemically induced
Pituitary Neoplasms pathology
Rats
Rats, Inbred F344
Reproducibility of Results
Carcinogens toxicity
Expectorants toxicity
Glycerol analogs & derivatives
Subjects
Details
- Language :
- English
- ISSN :
- 0273-2300
- Volume :
- 18
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Regulatory toxicology and pharmacology : RTP
- Publication Type :
- Academic Journal
- Accession number :
- 8278639
- Full Text :
- https://doi.org/10.1006/rtph.1993.1051