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[Mechanisms of ventricular tachycardia].

Authors :
Clémenty J
Cheradame I
Bordier P
Gosse P
Poquet F
Source :
Archives des maladies du coeur et des vaisseaux [Arch Mal Coeur Vaiss] 1993 May; Vol. 86 (5 Suppl), pp. 705-13.
Publication Year :
1993

Abstract

There are three fundamental mechanisms of ventricular tachycardia (VT) reentry, abnormal automaticity and triggered activity (TA) related to early or late after potentials. Reentry is certainly the mechanism of branch to branch and post-infarction VT. Early TA is responsible for Torsades de Pointes. Late TA is possibly the cause of certain verapamil-responsive VT but calcium-dependent reentry cannot be excluded. Abnormal automaticity or late TA may also play a role in catecholamine-induced VT. The development of drugs specific for the mechanism confronted with the results of programmed stimulation and mapping should improve the understanding of the mechanism of VT in each individual patient and allow more effective and better tolerated antiarrhythmic therapy.

Details

Language :
French
ISSN :
0003-9683
Volume :
86
Issue :
5 Suppl
Database :
MEDLINE
Journal :
Archives des maladies du coeur et des vaisseaux
Publication Type :
Academic Journal
Accession number :
8267497