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[Neoadjuvant chemotherapy effective for small cell lung cancer in a nephrectomized patient].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 1993 Nov; Vol. 20 (14), pp. 2235-8. - Publication Year :
- 1993
-
Abstract
- A 67-year-old man, who was nephrectomized due to renal cell cancer 4 years ago, was admitted to examine a mass shadow in the right middle lung field. He was diagnosed as small cell lung cancer with TBLB. Because of impaired renal function, he was treated with CBDCA (300 mg/m2, day 1), THP (30 mg/m2, day 1) and oral etoposide (25 mg/body, for 21 days) without any renal complications. After 3 courses of chemotherapy, the lung CT showed scar lesion despite the disappearance on the chest X-ray, and a right lower lobectomy was performed. Malignant cells remained in the scar lesion, but not in the lymph nodes. These findings suggested the effectiveness of neoadjuvant chemotherapy. This newly-designed chemotherapy procedure is necessary for patients with renal complications.
- Subjects :
- Aged
Carboplatin administration & dosage
Carcinoma, Renal Cell surgery
Chemotherapy, Adjuvant
Doxorubicin administration & dosage
Doxorubicin analogs & derivatives
Etoposide administration & dosage
Humans
Male
Neoplasms, Second Primary
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Carcinoma, Small Cell therapy
Lung Neoplasms therapy
Nephrectomy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 20
- Issue :
- 14
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 8239692