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[Neoadjuvant chemotherapy effective for small cell lung cancer in a nephrectomized patient].

Authors :
Toyoda T
Okamoto M
Fujii M
Yonezu S
Kumamoto T
Umemoto M
Saitoh Y
Okamura A
Source :
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 1993 Nov; Vol. 20 (14), pp. 2235-8.
Publication Year :
1993

Abstract

A 67-year-old man, who was nephrectomized due to renal cell cancer 4 years ago, was admitted to examine a mass shadow in the right middle lung field. He was diagnosed as small cell lung cancer with TBLB. Because of impaired renal function, he was treated with CBDCA (300 mg/m2, day 1), THP (30 mg/m2, day 1) and oral etoposide (25 mg/body, for 21 days) without any renal complications. After 3 courses of chemotherapy, the lung CT showed scar lesion despite the disappearance on the chest X-ray, and a right lower lobectomy was performed. Malignant cells remained in the scar lesion, but not in the lymph nodes. These findings suggested the effectiveness of neoadjuvant chemotherapy. This newly-designed chemotherapy procedure is necessary for patients with renal complications.

Details

Language :
Japanese
ISSN :
0385-0684
Volume :
20
Issue :
14
Database :
MEDLINE
Journal :
Gan to kagaku ryoho. Cancer & chemotherapy
Publication Type :
Academic Journal
Accession number :
8239692