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Experimental encephalomyocarditis virus infection in pigs.
- Source :
-
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B [Zentralbl Veterinarmed B] 1993 Jul; Vol. 40 (5), pp. 347-52. - Publication Year :
- 1993
-
Abstract
- A field isolate of Encephalomyocarditis (EMC) virus was inoculated intravenously into 8 pigs. Four animals died at post inoculation day (PID) 2, the remaining being sacrificed at PID 5, 7, 11 and 15. Two control, in-contact pigs were sacrificed at PID 19. Virus was isolated from leucocytes and nasal swabs until PID 4, from rectal swabs until PID 2 and, in the pigs found dead at PID 2, from several organs. EMC virus was further isolated from brain and spleen of the pig sacrificed at PID 7. One of the 2 control pigs became infected: virus was isolated from nasal swabs at days 6 and 7 and from leucocytes at day 4 of the experiment. Serum-neutralizing (SN) antibody was detected in the injected pigs starting from PID 4; two days later, it was also revealed in the infected, in-contact control. To our knowledge, this is the first report of an experimental transmission of EMC virus infection in pigs by contact exposure.
Details
- Language :
- English
- ISSN :
- 0514-7166
- Volume :
- 40
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B
- Publication Type :
- Academic Journal
- Accession number :
- 8237207
- Full Text :
- https://doi.org/10.1111/j.1439-0450.1993.tb00149.x