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[Prevention of post-ovariectomy osteoporosis in the rat. Comparative study of synthetic salmon calcitonin and eel calcitonin aminosuberic analogue].
- Source :
-
Minerva endocrinologica [Minerva Endocrinol] 1993 Sep; Vol. 18 (3), pp. 123-7. - Publication Year :
- 1993
-
Abstract
- The authors evaluate the efficacy of salmon calcitonin and aminosuberic analogue of eel calcitonin in the prevention of post-oophorectomy osteoporosis in rats. Both drugs, administered at the same dosage, are equally effective in preventing oophorectomy bone loss in rats. Besides, plasma biochemical evaluations demonstrate that calcitonins reduce bone turnover in treated rats, compared with control oophorectomized ones.
- Subjects :
- Absorptiometry, Photon
Alkaline Phosphatase blood
Animals
Biomarkers
Bone Resorption prevention & control
Calcitonin chemical synthesis
Calcium blood
Female
Humans
Osteocalcin blood
Ovariectomy adverse effects
Phosphorus blood
Rats
Rats, Sprague-Dawley
Calcitonin analogs & derivatives
Calcitonin therapeutic use
Osteoporosis, Postmenopausal prevention & control
Subjects
Details
- Language :
- Italian
- ISSN :
- 0391-1977
- Volume :
- 18
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Minerva endocrinologica
- Publication Type :
- Academic Journal
- Accession number :
- 8183179