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Salmonella infections in a cancer center.
- Source :
-
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer [Support Care Cancer] 1994 Mar; Vol. 2 (2), pp. 116-22. - Publication Year :
- 1994
-
Abstract
- Data concerning 40 patients hospitalized in a cancer center and Salmonella infection were analyzed. Hematological malignancy was present in 24 patients (60%) and solid tumor in 14 patients (35%). Among the predisposing factors, antineoplastic chemotherapy was the most frequent (60%) followed by antacid use (47.5%), corticosteroids (37.5%), granulocytopenia below 500 neutrophils/microliters (15%), surgery (10%) and splenectomy (2.5%). Bacteremia was the most frequent clinical syndrome accounting for 42.5% of the patients. Focal infection, enteritis and carrier state accounted for the remaining 30%, 20% and 7.5% respectively. Salmonella typhimurium and S. dublin represented 65% of the isolates, with clear association between serotype dublin and bacteremia. All S. dublin isolates were resistant to chloramphenicol. Among dublin and typhimurium serotypes, 20% the isolates were resistant to the traditional antibiotics used in salmonellosis (ampicillin, chloramphenicol, cotrimoxazole). All strains were susceptible in vitro to cephalosporins. The frequency of relapse was 15% and the overall mortality (within 30 days) attributed to Salmonella infection was 15%.
- Subjects :
- Adolescent
Adult
Aged
Bacteremia epidemiology
Belgium epidemiology
Cancer Care Facilities
Community-Acquired Infections epidemiology
Female
Focal Infection epidemiology
Humans
Male
Middle Aged
Neoplasms drug therapy
Neoplasms surgery
Recurrence
Salmonella isolation & purification
Salmonella Infections microbiology
Salmonella enteritidis isolation & purification
Salmonella typhimurium isolation & purification
Survival Rate
Neoplasms therapy
Salmonella Infections epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 0941-4355
- Volume :
- 2
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
- Publication Type :
- Academic Journal
- Accession number :
- 8156265
- Full Text :
- https://doi.org/10.1007/BF00572093