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[The value of duplex sonography after orthotopic liver transplantation. Experience with 44 patients].
- Source :
-
Langenbecks Archiv fur Chirurgie [Langenbecks Arch Chir] 1994; Vol. 379 (1), pp. 26-31. - Publication Year :
- 1994
-
Abstract
- In a prospective study, 44 patients (11 women, 33 men) who had received orthotopic liver transplants underwent a total of 196 consecutive duplex Doppler ultrasound examinations. The aim of the study was to evaluate the correlation between the pulsatile flow index (PFI) and the damping index (DI) as far as complications as rejection or cholangitis were concerned. The patients were examined five times each on average. The PFI and DI were measured in the hepatic artery, the portal vein and the hepatic veins. The findings were compared with the clinical course (cholangitis, rejection) and the histomorphological diagnosis as determined in biopsy specimens. In biopsy-proven rejection episodes, the sensitivity of the PFI in the hepatic artery was 69.4%, the specificity 72.2%. The sensitivity of the DI in the hepatic vein was 89.4%, the specificity 89.1%. Combining the two, specificity was more than 90%. PFI and DI in the portal vein bore no apparent relation to clinical course or histomorphological diagnosis. We found duplex Doppler ultrasound extremely beneficial in determining the timing and indication for liver biopsy. In addition, this simple examination, which can be performed as often as desired, accurately shows the transplanted liver's response to measures taken to counter rejection.
- Subjects :
- Adult
Aged
Blood Flow Velocity physiology
Constriction, Pathologic diagnostic imaging
Female
Graft Rejection diagnostic imaging
Hepatic Artery diagnostic imaging
Humans
Liver Function Tests
Male
Middle Aged
Pulsatile Flow physiology
Regional Blood Flow physiology
Ultrasonography
Vascular Resistance physiology
Ischemia diagnostic imaging
Liver blood supply
Liver Transplantation physiology
Postoperative Complications diagnostic imaging
Subjects
Details
- Language :
- German
- ISSN :
- 0023-8236
- Volume :
- 379
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Langenbecks Archiv fur Chirurgie
- Publication Type :
- Academic Journal
- Accession number :
- 8145614
- Full Text :
- https://doi.org/10.1007/BF00206558