Effect of depletion of glutathione by buthionine sulfoximine on lipid peroxidation in rats acutely treated with ethanol.

Authors :: Koçak-Toker N
Mutlu-Türkoğlu U
Alptekin N
Uysal M
Source :: The International journal of biochemistry [Int J Biochem] 1993 Dec; Vol. 25 (12), pp. 1765-8.
Publication Year :: 1993
Abstract: 1. The effect of depletion of glutathione (GSH) by DL-buthionine-S,R-sulfoximine (BSO) on lipid peroxidation in rats acutely treated with ethanol was investigated. 2. BSO pretreatment has not been found to potentiate an increase in liver, brain and erythrocyte lipid peroxide levels.

Subjects :: Animals
Brain drug effects
Brain metabolism
Buthionine Sulfoximine
Erythrocytes drug effects
Erythrocytes metabolism
Liver drug effects
Liver metabolism
Methionine Sulfoximine metabolism
Rats
Rats, Sprague-Dawley
Time Factors
Ethanol pharmacology
Glutathione deficiency
Lipid Peroxidation physiology
Methionine Sulfoximine analogs & derivatives

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