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Influences on weight loss in type 2 diabetic patients: little long-term benefit from group behaviour therapy and exercise training.
- Source :
-
Diabetic medicine : a journal of the British Diabetic Association [Diabet Med] 1994 Jun; Vol. 11 (5), pp. 449-57. - Publication Year :
- 1994
-
Abstract
- The aim of our study was to assess the long-term (24 months) efficacy of a comprehensive weight reduction programme as compared to that of a conventional programme. The Comprehensive Programme comprised, besides the Conventional Programme (diet counselling), behavioural modification and exercise training. The 2-year follow-up period was completed by 53 patients (19M/34F; 88.3%). The differences (95% confidence intervals; CI) between the change in body weight of patients in the Comprehensive Programme compared to the Conventional Programme after 6 and 24 months of treatment were -2.2 (-4.0, -0.3) kg, p = 0.03 and -1.3 (-3.3, 0.7) kg, p = 0.21, respectively. In comparison to the Conventional Programme, the Comprehensive Programme resulted in a greater decrease (95% CI) of HbA1c after 6 months: -0.8 (-1.2, -0.2)%, p = 0.01, but not after 2 years: -0.4 (-1.0, 0.1)%, p = 0.12. The effects on blood pressure and serum lipids of the Comprehensive Programme and the Conventional Programme were comparable. Changes in body weight at 6 months correlated well with changes in HbA1c, fasting plasma insulin, and blood pressure, whereas at 24 months no such correlation was found with HbA1c. Pretreatment variates that were associated with the greatest 2-year weight loss were a high HbA1c value, a low energy per cent carbohydrate intake and a low percentage of obese subjects within the family. In conclusion, the long-term outcome of the Comprehensive Programme was not different from that of the Conventional Programme. The achieved body weight reduction was associated with a sustained fall in blood pressure, but with only a transient beneficial effect on the glycaemic control in the Type 2 diabetic patient.
- Subjects :
- Adult
Aged
Blood Pressure physiology
Diabetes Mellitus blood
Diabetes Mellitus therapy
Diabetes Mellitus, Type 2 blood
Diabetes Mellitus, Type 2 therapy
Female
Humans
Male
Middle Aged
Predictive Value of Tests
Statistics as Topic
Time Factors
Behavior Therapy
Diabetes Mellitus physiopathology
Diabetes Mellitus, Type 2 physiopathology
Exercise
Obesity
Weight Loss physiology
Subjects
Details
- Language :
- English
- ISSN :
- 0742-3071
- Volume :
- 11
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Diabetic medicine : a journal of the British Diabetic Association
- Publication Type :
- Academic Journal
- Accession number :
- 8088122
- Full Text :
- https://doi.org/10.1111/j.1464-5491.1994.tb00305.x