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An unusual late reaction to Zyderm I injections: a challenge for treatment.
- Source :
-
Plastic and reconstructive surgery [Plast Reconstr Surg] 1993 Aug; Vol. 92 (2), pp. 331-4. - Publication Year :
- 1993
-
Abstract
- We describe a patient who, 2 1/2 years after injection with Zyderm I collagen, developed large erythematous indurated nodules and plaques at the facial injection sites. This occurred despite a prior negative skin test with the injectable material. Histopathologically, a sarcoid-like foreign-body reaction was present in the dermis and subcutaneous fat and muscles. Retesting with Zyderm I collagen on the forearm produced a positive reaction that showed, histologically, a sarcoid-like reaction similar to that which was found in the face. Various modes of therapy have failed to clear the facial lesions and disfigurement.
Details
- Language :
- English
- ISSN :
- 0032-1052
- Volume :
- 92
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Plastic and reconstructive surgery
- Publication Type :
- Academic Journal
- Accession number :
- 8068054
- Full Text :
- https://doi.org/10.1097/00006534-199308000-00021