[Adaptation to alternating exercise and cold as a factor in the prevention of disorders of cardiac rhythm and contractile activity in acute myocardial ischemia in rats].

Occlusion of the left coronary artery under general anesthesia and reperfusion were conducted in male Wistar rats adapted to cold, exercise during swimming and to the alternation of these effects. Adaptation facilitated reduction in the occurrence of arrhythmias and depression of contractile activity of the heart under these conditions. Although among the three types of adaptational effects, exercise induced the most marked development of the myocardial capillary network, its alternation with cold prevented more effectively the development of disorders of heart rhythm and contractility caused by ischemia and reperfusion.