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[The use of nimodipine in the acute period of a cerebral infarct].
- Source :
-
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 1993; Vol. 93 (3), pp. 15-8. - Publication Year :
- 1993
-
Abstract
- Before and after intravenous administration of 1-1.5 mg nimotop 18 patients with acute brain infarction underwent EEG, integral body rheography, computed tomography and measurement of regional volumetric cerebral circulation (RVCC). Nimotop appeared to increase RVCC in the infarction zone, especially in low initial RVCC levels. The drug induced a shift to EEG normalization and a hypotensive effect, cerebral hemodynamics remaining without changes. Nimodipine-type calcium antagonists favourably affect brain perfusion and bioelectric activity which is promising for application in acute cerebral infarction.
- Subjects :
- Acute Disease
Adult
Aged
Brain diagnostic imaging
Brain drug effects
Brain physiopathology
Cerebral Infarction diagnostic imaging
Cerebral Infarction physiopathology
Cerebrovascular Circulation drug effects
Drug Evaluation
Electroencephalography drug effects
Female
Hemodynamics drug effects
Humans
Male
Middle Aged
Tomography, X-Ray Computed
Cerebral Infarction drug therapy
Nimodipine therapeutic use
Subjects
Details
- Language :
- Russian
- ISSN :
- 1997-7298
- Volume :
- 93
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
- Publication Type :
- Academic Journal
- Accession number :
- 8042382