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Mutagenicity of B(a)P in the presence of some hydralazine derivatives.
- Source :
-
Polish journal of occupational medicine and environmental health [Pol J Occup Med Environ Health] 1993; Vol. 6 (4), pp. 383-9. - Publication Year :
- 1993
-
Abstract
- Hydralazine, dihydralazine and todralazine were tested in the aspect of their mutagenic potency, and the influence upon the mutagenicity of standard promutagen--B(a)P. Hydralazine exhibited strong mutagenic activity in the Ames test while mutagenic activity of dihydralazine was relatively weak. Todralazine had no mutagenic activity, and significantly decreased mutagenicity of B(a)P. It was concluded that todralazine could be a good antimutagenic substance.
Details
- Language :
- English
- ISSN :
- 0867-8383
- Volume :
- 6
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Polish journal of occupational medicine and environmental health
- Publication Type :
- Academic Journal
- Accession number :
- 8019200