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[The use of monoclonal antibodies for detecting the influenza virus].

Authors :
Bakova AA
Brondz BD
Fedorkina OA
Gusev VA
Gordienko AI
Krivoshein IuS
Krivorutchenko IuL
Prokopenko TG
Popov IA
Source :
Voprosy virusologii [Vopr Virusol] 1994 Jul-Aug; Vol. 39 (4), pp. 187-9.
Publication Year :
1994

Abstract

The possibilities of using influenza A (Leningrad) 385/80 (H3N2) virus matrix protein-specific FITC-labeled D8 monoclonal antibodies in immunofluorescence assays were investigated. The virus antigen accumulation was detected in chorioallantoic cells of chick embryos. Exhibiting the type-specific properties, the fluorescent antibodies stain the perinuclear space, cytoplasmic membrane, and granular structures in the cytoplasm of infected cells. The haemagglutination test tires in the corresponding specimens were at least 1:16.

Details

Language :
Russian
ISSN :
0507-4088
Volume :
39
Issue :
4
Database :
MEDLINE
Journal :
Voprosy virusologii
Publication Type :
Academic Journal
Accession number :
7998401