Back to Search
Start Over
Does thrombolysis affect the prognostic value of the post-infarct exercise test?
- Source :
-
International journal of cardiology [Int J Cardiol] 1994 Nov; Vol. 47 (1), pp. 13-20. - Publication Year :
- 1994
-
Abstract
- There has been some debate on usefulness of the exercise test in risk stratification after myocardial infarction in the thrombolytic era. This was assessed in 295 patients of whom 184 were treated with thrombolysis. Each had an exercise test using a modified Naughton protocol within 14 days of acute myocardial infarction. The tests were graded as high risk positive (112), low risk positive (83), or negative (100). These gradings predicted use of multiple drug therapy (p = 0.05), severity of coronary artery disease (p < 0.01), and coronary artery bypass grafting (p < 0.01). There was no influence on heart failure, recurrent myocardial infarction or death. This was independent of the use of thrombolytic therapy. The whole group had a good prognosis with a mortality of 2.4% after 56 weeks' follow-up. The exercise test is still a useful screening test after myocardial infarction. In this study, there was a high negative predictive accuracy of 91% for any event. Its use is not altered by thrombolysis. The finding of a lack of influence of the exercise test on major events may be a reflection of the current good prognosis after myocardial infarction and the prompt use of revascularisation.
- Subjects :
- Adult
Aged
Female
Humans
Male
Middle Aged
Myocardial Infarction mortality
Myocardial Infarction physiopathology
Prognosis
Retrospective Studies
Risk Factors
Sensitivity and Specificity
Exercise Test drug effects
Myocardial Infarction drug therapy
Streptokinase therapeutic use
Thrombolytic Therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0167-5273
- Volume :
- 47
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- International journal of cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 7868280
- Full Text :
- https://doi.org/10.1016/0167-5273(94)90128-7