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Plasma proteins in the period of posttransfusion polycythaemia in rats.
- Source :
-
Acta physiologica Polonica [Acta Physiol Pol] 1978 Jan-Feb; Vol. 29 (1), pp. 47-54. - Publication Year :
- 1978
-
Abstract
- Plasma proteins in the period of post-transfusion polycythaemia in rats. Acta Physiol. Pol., 1978, 29 (1): 47-54. The plasma protein of polycythaemic rats with strongly inhibited erythropoiesis and of normal rats was characterized with the use of ion exchanger chromatography on DEAE-cellulose in an NaCl concentration gradient and electrophoresis on polyacrylamide gel. Experimental posttransfusion polycythaemia was found to cause considerable changes in the amount and composition of plasma proteins. The amount of gamma and alpha1 globulins increased in polycythaemic animals, whereas albumin content decreased. There also appeared wide differences in the elution profiles obtained from ion exchanger chromatography of both kinds of plasma. Electrophoretic analysis of fractions obtained by chromatography demonstrated a similarity only in the composition of the globulin fractions of both the plasma kinds. The remaining fractions differed widely in their protein composition.
Details
- Language :
- English
- ISSN :
- 0044-6033
- Volume :
- 29
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Acta physiologica Polonica
- Publication Type :
- Academic Journal
- Accession number :
- 78660