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Major gene for percent of oxygen saturation of arterial hemoglobin in Tibetan highlanders.
- Source :
-
American journal of physical anthropology [Am J Phys Anthropol] 1994 Nov; Vol. 95 (3), pp. 271-6. - Publication Year :
- 1994
-
Abstract
- This report employs a statistical genetic approach to analyze quantitative oxygen transport variables in a high-altitude (4,850-5,450 m) native Tibetan population and demonstrates the presence of a major gene influencing % O2 saturation of arterial hemoglobin. This result suggests the hypothesis that individuals with the dominant allele for higher % O2 saturation have a selective advantage at high altitude. Studies of the biologically distinctive Himalayan and Andean populations have greatly influenced thinking about ongoing human evolution and adaptation; this is the first statistical evidence for a major gene enhancing oxygen transport in a high-altitude native population.
Details
- Language :
- English
- ISSN :
- 0002-9483
- Volume :
- 95
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- American journal of physical anthropology
- Publication Type :
- Academic Journal
- Accession number :
- 7856765
- Full Text :
- https://doi.org/10.1002/ajpa.1330950303