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A fetus with sirenomelia, omphalocele, and meningomyelocele, but normal kidneys.

Authors :
McCoy MC
Chescheir NC
Kuller JA
Altman GC
Flannagan LM
Source :
Teratology [Teratology] 1994 Aug; Vol. 50 (2), pp. 168-71.
Publication Year :
1994

Abstract

Sirenomelia, which has been reported for more than 450 years, is the most severe form of caudal dysplasia. This disorder is classically associated with agenesis or severe dysplasia of the urinary tract. A 27-year-old gravida 3 para 0020 presented at 19 weeks' gestation with monoamniotic twins, one normal and one with sirenomelia. The pregnancy miscarried following invasive diagnostic testing. Autopsy confirmed the findings of sirenomelia, meningomyelocele, omphalocele, persistent cloaca, and two normal kidneys. The abnormalities accompanying sirenomelia appear as a spectrum. The pathogenic theories of sirenomelia are reviewed in light of this case with normal kidneys.

Details

Language :
English
ISSN :
0040-3709
Volume :
50
Issue :
2
Database :
MEDLINE
Journal :
Teratology
Publication Type :
Academic Journal
Accession number :
7801305
Full Text :
https://doi.org/10.1002/tera.1420500212