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The human immunoglobulin VH repertoire.

Authors :
Cook GP
Tomlinson IM
Source :
Immunology today [Immunol Today] 1995 May; Vol. 16 (5), pp. 237-42.
Publication Year :
1995

Abstract

A complete map of the human immunoglobulin VH locus on chromosome 14 has recently been constructed. The locus is 1100kb in length and contains 51 functional VH segments interspersed amongst a similar number of pseudogenes. Here, Graham Cook and Ian Tomlinson review the organization of the locus, its polymorphism and the repertoire it encodes.

Subjects

Subjects :
Chromosome Mapping
Humans
Polymorphism, Genetic genetics
Pseudogenes genetics
Chromosomes, Human, Pair 14 genetics
Immunoglobulin Variable Region genetics

Details

Language :
English
ISSN :
0167-5699
Volume :
16
Issue :
5
Database :
MEDLINE
Journal :
Immunology today
Publication Type :
Academic Journal
Accession number :
7779254
Full Text :
https://doi.org/10.1016/0167-5699(95)80166-9
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