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Indications for immediate angiotensin-converting enzyme inhibition in patients with acute myocardial infarction.
- Source :
-
Journal of the American College of Cardiology [J Am Coll Cardiol] 1995 Jun; Vol. 25 (7 Suppl), pp. 47S-51S. - Publication Year :
- 1995
-
Abstract
- When initiated a few days after myocardial infarction, angiotensin-converting enzyme inhibition exerts beneficial effects on survival and morbidity in patients with asymptomatic left ventricular systolic dysfunction or symptomatic heart failure. During the acute phase of a myocardial infarction, angiotensin-converting enzyme inhibition appears to be well tolerated, to prevent the development of heart failure in patients with asymptomatic left ventricular systolic dysfunction and to improve the hemodynamic and clinical variables of heart failure when present. Accordingly, early angiotensin-converting enzyme inhibition is clearly indicated in patients with acute myocardial infarction associated with asymptomatic left ventricular dysfunction or clinical evidence of heart failure. Angiotensin-converting enzyme inhibition may also be beneficial when thrombolytic agents fail to restore coronary patency in patients with acute myocardial infarction.
- Subjects :
- Angiotensin-Converting Enzyme Inhibitors administration & dosage
Angiotensin-Converting Enzyme Inhibitors adverse effects
Heart Failure etiology
Hemodynamics drug effects
Humans
Hypotension chemically induced
Myocardial Infarction physiopathology
Randomized Controlled Trials as Topic
Time Factors
Ventricular Dysfunction, Left etiology
Angiotensin-Converting Enzyme Inhibitors therapeutic use
Heart Failure drug therapy
Myocardial Infarction complications
Ventricular Dysfunction, Left drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0735-1097
- Volume :
- 25
- Issue :
- 7 Suppl
- Database :
- MEDLINE
- Journal :
- Journal of the American College of Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 7775715
- Full Text :
- https://doi.org/10.1016/0735-1097(95)00103-b