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[Somatostatin receptor scintigraphy in medullary thyroid carcinomas, GEP and carcinoid tumors].
- Source :
-
Nuklearmedizin. Nuclear medicine [Nuklearmedizin] 1995 Feb; Vol. 34 (1), pp. 1-7. - Publication Year :
- 1995
-
Abstract
- For this study, 24 patients with medullary thyroid cancer (MTC) and 10 with carcinoid-/GEP-tumours underwent scintigraphy with 123I-Tyr3-octreotide or 111In-DTPA-D-Phe1-octreotide (Octreoscan) or 99mTc-V-DMSA. Calcitonin and CEA were elevated in MTC patients, the other had tumour lesions on CT. Octreoscan-scintigraphy was positive in 68% of all suspicious cases. On the other hand, 123I-Tyr3-octreotide showed only rarely positive results. 99mTc-V-DMSA-scans in MTC patients were positive in 23%. Liver metastases could be seen only with Octreoscan in the non-MTC-group. These results showed better sensitivity of 111In-labelled octreotide.
- Subjects :
- Adult
Aged
Calcitonin analysis
Carcinoembryonic Antigen analysis
Carcinoma, Medullary secondary
False Positive Reactions
Female
Humans
Indium Radioisotopes
Iodine Radioisotopes
Liver Neoplasms diagnostic imaging
Liver Neoplasms secondary
Male
Middle Aged
Octreotide analogs & derivatives
Organotechnetium Compounds
Pentetic Acid analogs & derivatives
Radionuclide Imaging
Sensitivity and Specificity
Succimer
Technetium Tc 99m Dimercaptosuccinic Acid
Carcinoid Tumor diagnostic imaging
Carcinoma, Medullary diagnostic imaging
Gastrointestinal Neoplasms diagnostic imaging
Pancreatic Neoplasms diagnostic imaging
Receptors, Somatostatin analysis
Thyroid Neoplasms diagnostic imaging
Subjects
Details
- Language :
- German
- ISSN :
- 0029-5566
- Volume :
- 34
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Nuklearmedizin. Nuclear medicine
- Publication Type :
- Academic Journal
- Accession number :
- 7724358