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Chronic pneumomediastinum and subcutaneous emphysema: association with dermatomyositis.
- Source :
-
Respiration; international review of thoracic diseases [Respiration] 1995; Vol. 62 (1), pp. 53-6. - Publication Year :
- 1995
-
Abstract
- We describe a 41-year-old patient with adult-onset dermatomyositis who developed persistent pneumomediastinum and severe subcutaneous emphysema due to end-stage interstitial lung disease. The diagnosis of dermatomyositis was based on proximal muscle weakness, electromyographic findings of inflammatory myopathy, and positive findings on muscle biopsy. Low levels of creatine kinase elevation were found at the time of diagnosis (a form of dermatomyositis which has been associated with a poor prognosis). The patient had no signs of cutaneous vasculitis. Despite treatment with prednisone and azathioprine, she died of intercurrent gram-negative sepsis 15 months after the diagnosis of dermatomyositis.
- Subjects :
- Adult
Age of Onset
Biopsy, Needle
Bronchoscopy
Chronic Disease
Dermatomyositis diagnosis
Dermatomyositis drug therapy
Fatal Outcome
Female
Humans
Lung Diseases, Interstitial diagnosis
Lung Diseases, Interstitial therapy
Mediastinal Emphysema diagnosis
Mediastinal Emphysema therapy
Prednisone therapeutic use
Subcutaneous Emphysema diagnosis
Subcutaneous Emphysema therapy
Thoracotomy
Dermatomyositis complications
Lung Diseases, Interstitial complications
Mediastinal Emphysema etiology
Subcutaneous Emphysema etiology
Subjects
Details
- Language :
- English
- ISSN :
- 0025-7931
- Volume :
- 62
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Respiration; international review of thoracic diseases
- Publication Type :
- Academic Journal
- Accession number :
- 7716358
- Full Text :
- https://doi.org/10.1159/000196390