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Epidemiological, clinical and microbiological features of shigellosis among hospitalized children in northern Israel.
- Source :
-
Scandinavian journal of infectious diseases [Scand J Infect Dis] 1995; Vol. 27 (2), pp. 139-44. - Publication Year :
- 1995
-
Abstract
- The epidemiological, clinical, and bacteriological aspects of shigellosis were studied in a population of hospitalized children in northern Israel. During the 6-year period 1987-92, 262 children were hospitalized due to shigella infection. Shigellosis represented 10% of pediatric admissions for diarrhea. Admissions for the disease peaked during the summer and autumn. The median age of the patients was 3 years. Shigella sonnei was isolated in 74% of patients and S. flexneri in 21%, compared with relative frequencies of 87% and 10%, respectively, in the non-hospitalized population of the area, detected during the same period (p < 0.001). Shigella sonnei represented 82% of isolates of hospitalized Jewish patients but only 60% of hospitalized Arab children, many of whom live in poverty and overcrowding (p < 0.001). Shigella flexneri was particularly frequent among hospitalized infants, and was associated with Arab origin, large families and residence in agricultural settlements. Duration of hospitalization was 4.7 +/- 2.3 days for S. sonnei infections and 5.8 +/- 3.6 days for S. flexneri (p < 0.005). No cases of shigella sepsis, hemolytic uremic syndrome, or fatalities were observed. Overall 37% of all shigella isolates from hospitalized children were resistant to ampicillin, 71% to cotrimoxazole, 28% to both and 13% were resistant to > or = 3 different drugs. It is concluded that shigellosis is an important cause of hospitalization in northern Israel. Resistance to antimicrobial drugs is widespread among all Shigella spp. Although S. sonnei is the most common species, S. flexneri is particularly frequent in infants.
- Subjects :
- Adolescent
Anti-Bacterial Agents pharmacology
Arab World
Child
Child, Preschool
Diarrhea epidemiology
Diarrhea microbiology
Diarrhea pathology
Drug Resistance, Microbial
Dysentery, Bacillary microbiology
Dysentery, Bacillary pathology
Dysentery, Bacillary therapy
Feces microbiology
Female
Humans
Infant
Infant, Newborn
Israel epidemiology
Jews
Length of Stay
Male
Microbial Sensitivity Tests
Retrospective Studies
Seasons
Shigella flexneri drug effects
Shigella sonnei drug effects
Dysentery, Bacillary epidemiology
Hospitalization statistics & numerical data
Shigella flexneri isolation & purification
Shigella sonnei isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 0036-5548
- Volume :
- 27
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Scandinavian journal of infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 7660077
- Full Text :
- https://doi.org/10.3109/00365549509018994