The cDNA encoding Xenopus laevis heat-shock factor 1 (XHSF1): nucleotide and deduced amino-acid sequences, and properties of the encoded protein.

Authors :: Stump DG
Landsberger N
Wolffe AP
Source :: Gene [Gene] 1995 Jul 28; Vol. 160 (2), pp. 207-11.
Publication Year :: 1995
Abstract: We have isolated a cDNA encoding Xenopus laevis (Xl) heat-shock factor 1 (XHSF1). XHSF1, translated from the mRNA synthesized in vitro, will bind specifically to the Xl hsp70 promoter (hsp70). Microinjection of XHSF1 mRNA into Xl oocytes leads to synthesis of XHSF1 which accumulates in the nucleus and selectively activates Xl phsp70p activity at 18 degrees C.

Subjects :: Amino Acid Sequence
Animals
Base Sequence
Cell Nucleus metabolism
DNA, Complementary genetics
Heat Shock Transcription Factors
Molecular Sequence Data
Recombinant Fusion Proteins metabolism
Sequence Alignment
Sequence Homology, Amino Acid
Transcription Factors
Transcription, Genetic
DNA-Binding Proteins genetics
Genes
Xenopus laevis genetics

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