Endogenous histamine induces c-fos expression within paraventricular and supraoptic nuclei.

Authors :: Vizuete ML
Dimitriadou V
Traiffort E
Griffon N
Heron A
Schwartz JC
Source :: Neuroreport [Neuroreport] 1995 May 09; Vol. 6 (7), pp. 1041-4.
Publication Year :: 1995
Abstract: Thioperamide, an H3-receptor antagonist that enhances endogenous histamine release, induced c-fos mRNA expression and Fos-like immunoreactivity in magnocellular neurones of rat supraoptic and paraventricular nuclei. This response was prevented as a result of blockade of the H1 receptor, indicating that endogenous histamine is able to activate these magnocellular neurones via stimulation of this receptor.

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