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Thyroglobulin in benign and malignant thyroid disease.

Authors :
Gerfo PL
Colacchio T
Colacchio D
Feind C
Source :
JAMA [JAMA] 1979 Mar 02; Vol. 241 (9), pp. 923-4.
Publication Year :
1979

Abstract

Thyroglobulin (TG) is a 19S glycoprotein produced by normal thyroids and almost all nonmedullary thyroid cancers. Radioimmunoassays measure serum levels of TG, and these levels are abnormally elevated in patients with metastatic thyroid cancer. Data from our study show that TG measurement is not effective in screening high-risk populations for thyroid cancer. Nevertheless, serum TG determinations are useful for assessing the presence and possibly the extent of residual or recurrent nonmedullary thyroid cancer in patients who have undergone total thyroidectomy.

Details

Language :
English
ISSN :
0098-7484
Volume :
241
Issue :
9
Database :
MEDLINE
Journal :
JAMA
Publication Type :
Academic Journal
Accession number :
762873