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Neurophysiological examination of end-plate function in patients with lung cancer.
- Source :
-
Electromyography and clinical neurophysiology [Electromyogr Clin Neurophysiol] 1995 Jun-Jul; Vol. 35 (4), pp. 247-50. - Publication Year :
- 1995
-
Abstract
- Twenty-eight patients affected by lung cancer were studied with neurophysiological and clinical examinations to show the prevalence of alteration of neuromuscular transmission. During repetitive stimulation at 20 Hz we found in 6 cases (22%) an increment (> 20%) and in 4 cases a decrement ( > 10%) of the size of muscle action potentials. In 15 patients (57%) we found low sensory action potential amplitude (< 11 uv). In 3 (11%) of the 6 cases with incremental response the overall examination suggested a disorder of neuromuscular junction such as Eaton-Lambert syndrome. Our results suggest that the peripheral nervous system involvement in patients affected by lung cancer is higher than usually estimated.
- Subjects :
- Action Potentials physiology
Adult
Aged
Female
Humans
Male
Median Nerve
Middle Aged
Muscles physiopathology
Neuromuscular Junction physiology
Synaptic Transmission physiology
Ulnar Nerve
Adenocarcinoma physiopathology
Carcinoma, Small Cell physiopathology
Carcinoma, Squamous Cell physiopathology
Lung Neoplasms physiopathology
Motor Endplate physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 0301-150X
- Volume :
- 35
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Electromyography and clinical neurophysiology
- Publication Type :
- Academic Journal
- Accession number :
- 7555930