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Further characterization of the 5'-flanking region of the rat lactase-phlorizin hydrolase gene.
Further characterization of the 5'-flanking region of the rat lactase-phlorizin hydrolase gene.
- Source :
-
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 1995 Apr 26; Vol. 209 (3), pp. 989-95. - Publication Year :
- 1995
-
Abstract
- The lactase-phlorizin hydrolase gene is widely used as a marker of intestinal differentiation. Recent evidence demonstrating that transcription plays a major role in the regulation of this gene suggests that study of the 5'-flanking region will allow an understanding of how the expression of this gene is controlled. However, sequence, restriction, and primer extension analysis of a rat genomic clone has revealed that previously published data are incomplete. In the present study, we used a directed sequencing strategy to carefully analyze this region. Our expanded analysis of the 5'-flanking region of the lactase-phlorizin hydrolase gene should facilitate future studies of its structure and function.
Details
- Language :
- English
- ISSN :
- 0006-291X
- Volume :
- 209
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Biochemical and biophysical research communications
- Publication Type :
- Academic Journal
- Accession number :
- 7537502
- Full Text :
- https://doi.org/10.1006/bbrc.1995.1595