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Rat connexins 30.3 and 31 are expressed in the kidney.
- Source :
-
Experimental cell research [Exp Cell Res] 1994 Jul; Vol. 213 (1), pp. 224-30. - Publication Year :
- 1994
-
Abstract
- Six connexin genes have previously been shown to be expressed in the rat kidney. Given the structural and functional diversity of the kidney, we hypothesize that other connexin genes may be expressed. We have partially screened a rat kidney cDNA library using low-stringency hybridization conditions with cDNA probes from rCx 43 and rCx 26 and report here the isolation of two connexin cDNA clones, rCx 30.3 and rCx 31, that have not previously been shown to be expressed in the rat kidney. Furthermore, rCx 30.3 utilizes two distinct transcripts in the kidney, while rCx 31 utilizes two transcripts in skin but only one in the kidney.
- Subjects :
- Amino Acid Sequence
Animals
Base Sequence
Blotting, Northern
Blotting, Southern
Cloning, Molecular
DNA blood
DNA metabolism
DNA, Complementary isolation & purification
DNA, Complementary metabolism
Molecular Sequence Data
Organ Specificity
Poly A biosynthesis
Poly A isolation & purification
RNA biosynthesis
RNA isolation & purification
RNA, Messenger
Rats
Restriction Mapping
Sequence Homology, Amino Acid
Sequence Homology, Nucleic Acid
Transcription, Genetic
Connexins biosynthesis
Gene Expression
Kidney metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 0014-4827
- Volume :
- 213
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Experimental cell research
- Publication Type :
- Academic Journal
- Accession number :
- 7517368
- Full Text :
- https://doi.org/10.1006/excr.1994.1194