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Small gliomas: metabolism and blood flow.
- Source :
-
Neurologia medico-chirurgica [Neurol Med Chir (Tokyo)] 1994 Feb; Vol. 34 (2), pp. 91-4. - Publication Year :
- 1994
-
Abstract
- Eight patients with small gliomas (6 low-grade and 2 high-grade) localized in a single gyrus or less than 2 cm diameter were investigated using positron emission tomography and single photon emission computed tomography. All three tumors examined demonstrated hypermetabolism of amino acids. High-grade gliomas demonstrated hypermetabolism of glucose and high blood flow, but normal or low oxygen metabolism. High-grade gliomas also showed accumulation of 201Tl chloride and high or low accumulation of 123I-isopropyl iodoamphetamine. These indications allow preoperative diagnosis of the malignancy of small gliomas, which is important because small gliomas with high-grade malignancy need more extensive removal and adjuvant therapy.
- Subjects :
- Adult
Astrocytoma diagnostic imaging
Astrocytoma pathology
Cerebral Cortex blood supply
Cerebral Cortex diagnostic imaging
Cerebral Cortex pathology
Child
Female
Glioblastoma diagnostic imaging
Glioblastoma pathology
Humans
Male
Middle Aged
Neoplasm Staging
Prognosis
Regional Blood Flow physiology
Supratentorial Neoplasms diagnostic imaging
Supratentorial Neoplasms pathology
Astrocytoma blood supply
Energy Metabolism physiology
Glioblastoma blood supply
Supratentorial Neoplasms blood supply
Tomography, Emission-Computed
Tomography, Emission-Computed, Single-Photon
Subjects
Details
- Language :
- English
- ISSN :
- 0470-8105
- Volume :
- 34
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Neurologia medico-chirurgica
- Publication Type :
- Academic Journal
- Accession number :
- 7514763
- Full Text :
- https://doi.org/10.2176/nmc.34.91