[The clinical manifestations of herpetic stomatitis in children with acute lymphoblastic leukemia].

Clinical (n = 137) and virological (n = 50) analysis of the course of herpetic stomatitis in children with acute lymphoblastic leukemia was carried out. 97.8 +/- 1.4% of cases were relapses of a chronic herpetic infection, 73.8 +/- 3.7% of cases ran a medium severe or severe course. Herpetic stomatitis in children suffering from acute lymphoblastic leukemia was characterized by the following features: 1) a high risk of infection generalization; 2) progressive necrosis of tissues in a state of leukopenia; 3) infiltration at the site of necrosis; 4) tissue anemia; and 5) risk of hemorrhage from necrotic sites.