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Validation of a modified 28-day rat study to evidence effects of test compounds on the immune system.
- Source :
-
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 1995 Aug; Vol. 22 (1), pp. 54-6. - Publication Year :
- 1995
- Subjects :
- Animals
Female
Hemolytic Plaque Technique
Humans
Immune System pathology
Immunoglobulin G biosynthesis
Immunoglobulin G blood
Immunoglobulin G drug effects
Immunoglobulin M biosynthesis
Immunoglobulin M blood
Immunoglobulin M drug effects
Immunophenotyping
Kidney drug effects
Kidney pathology
Killer Cells, Natural immunology
Liver drug effects
Liver pathology
Lymphocyte Activation drug effects
Lymphoid Tissue drug effects
Lymphoid Tissue pathology
Macrophage Activation drug effects
Male
Mitogens pharmacology
Rats
Rats, Wistar
Cyclosporine toxicity
Immune System drug effects
Toxicity Tests standards
Subjects
Details
- Language :
- English
- ISSN :
- 0273-2300
- Volume :
- 22
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Regulatory toxicology and pharmacology : RTP
- Publication Type :
- Academic Journal
- Accession number :
- 7494903
- Full Text :
- https://doi.org/10.1006/rtph.1995.1068