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Uterotonic effect of Evodia rutaecarpa alkaloids.
- Source :
-
Journal of natural products [J Nat Prod] 1980 Sep-Oct; Vol. 43 (5), pp. 577-82. - Publication Year :
- 1980
-
Abstract
- Rutaecarpine (1) and dehydroevodiamine (2) were isolated from the unripe fruit of Evodia rutaecarpa. In vitro uterotonic assay on rat uterus showed both alkaloids to be active. Dehydroevodiamine was further shown to be active in the in vivo uterotonic assay using rats as the animal model. Reference evodiamine hydrochloride (3) was also evaluated and found to be devoid of uterontonic activity at the doses administered.
Details
- Language :
- English
- ISSN :
- 0163-3864
- Volume :
- 43
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Journal of natural products
- Publication Type :
- Academic Journal
- Accession number :
- 7463094
- Full Text :
- https://doi.org/10.1021/np50011a008