Back to Search
Start Over
"Navajo arthritis" reconsidered: relationship to HLA-B27.
- Source :
-
Arthritis and rheumatism [Arthritis Rheum] 1980 Nov; Vol. 23 (11), pp. 1299-1302. - Publication Year :
- 1980
-
Abstract
- "Navajo arthritis" was described in 1971 as an acute, self-limited, asymmetric polyarthritis of unknown etiology seen in Navajo Indian patients. This description was before published accounts relating HLA-B27 to certain seronegative arthropathies. Review of 92 cases of arthritis seen between 1977 through 1979 in adult Navajo Indians revealed 16 cases of complete Reiter's syndrome, 6 cases of incomplete Reiter's syndrome, and 7 cases of ankylosing spondylitis. The phenotype frequency of HLA-B27 in this Navajo population is 36% and, of the Reiter's syndrome and ankylosing spondylitis patients tested, 85% were found to be HLA-B27 positive. We suggest that "Navajo arthritis" may not be a unique form of arthritis affecting only the Navajo, but a variant of either Reiter's syndrome or ankylosing spondylitis.
Details
- Language :
- English
- ISSN :
- 0004-3591
- Volume :
- 23
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Arthritis and rheumatism
- Publication Type :
- Academic Journal
- Accession number :
- 7447964
- Full Text :
- https://doi.org/10.1002/art.1780231112