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Toxic properties of an isomer of halothane.

Authors :
Cascorbi HF
Vento JM
Source :
Der Anaesthesist [Anaesthesist] 1980 Apr; Vol. 29 (4), pp. 169-71.
Publication Year :
1980

Abstract

1,1,2-trifluoro-1-bromo-2-chloro ethane, an isomer of halothane, was tested for its anesthetic and toxic properties in rats. The isomer is about one-half as potent as halothane and is metabolized to a lethal compound.

Subjects

Subjects :
Animals
Biotransformation
Dogs
Drug Administration Schedule
Drug Interactions
Fluorides blood
Isomerism
Male
Mice
Rats
Structure-Activity Relationship
Halothane toxicity

Details

Language :
English
ISSN :
0003-2417
Volume :
29
Issue :
4
Database :
MEDLINE
Journal :
Der Anaesthesist
Publication Type :
Academic Journal
Accession number :
7425246

Tools

Authors Abstract Subjects Details