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A fixed combination of hydrochlorothiazide and amiloride for the treatment of essential hypertension.
- Source :
-
Clinical therapeutics [Clin Ther] 1980; Vol. 3 (1), pp. 15-20. - Publication Year :
- 1980
-
Abstract
- The combination of hydrochlorothiazide and amiloride has been used in a group of patients diagnosed as having essential hypertension. Sixty-five percent of the patients for whom dietary restrictions did not achieve a reduction in blood pressure were initially controlled with this combination; the addition of a second or third drug was required by the remaining patients. During the six-month follow-up, the control of blood pressure was satisfactory with increased drug requirements, but the diuretic had to be discontinued in 12 patients because of side effects.
- Subjects :
- Adolescent
Adult
Aged
Amiloride adverse effects
Blood Chemical Analysis
Blood Pressure drug effects
Body Weight drug effects
Drug Therapy, Combination
Female
Gastrointestinal Diseases chemically induced
Humans
Hydrochlorothiazide adverse effects
Hyperglycemia chemically induced
Male
Middle Aged
Uric Acid blood
Amiloride administration & dosage
Hydrochlorothiazide administration & dosage
Hypertension drug therapy
Pyrazines administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 0149-2918
- Volume :
- 3
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Clinical therapeutics
- Publication Type :
- Academic Journal
- Accession number :
- 7407819