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Toxicological studies of liver cells by microspectrofluorometry.

Authors :
Stier A
Nolte KH
Schlenker A
Schumann W
Zuretti FM
Source :
Archives of toxicology [Arch Toxicol] 1980 Mar; Vol. 44 (1-3), pp. 45-54.
Publication Year :
1980

Abstract

The kinetics of xenobiotic biotransformation was measured in single, isolated, perifused liver cells with microspectrofluorometry using highly sensitive photodetection systems. A program of further applications to biochemical toxicological problems is presented.

Subjects

Subjects :
Animals
Biotransformation
In Vitro Techniques
Kinetics
Liver cytology
Male
Microchemistry
Mixed Function Oxygenases metabolism
NAD metabolism
NADP metabolism
Oxazines metabolism
Photochemistry
Rats
Spectrometry, Fluorescence
Toxicology
Liver metabolism
Pharmaceutical Preparations metabolism

Details

Language :
English
ISSN :
0340-5761
Volume :
44
Issue :
1-3
Database :
MEDLINE
Journal :
Archives of toxicology
Publication Type :
Academic Journal
Accession number :
7387402
Full Text :
https://doi.org/10.1007/BF00303182
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