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[Isolation and characteristics of the messenger RNA of an interferon repressor].
- Source :
-
Antibiotiki [Antibiotiki] 1980 Mar; Vol. 25 (3), pp. 215-8. - Publication Year :
- 1980
-
Abstract
- The methods of induction, isolation and testing of the functional activity of the informative RNA of the interferon production repressor were developed. The repressor informative RNA was found in the cells an hour after the repeated induction of interferon. The minimal time of its translation, i.e. 25--30 minutes was determined. It was shown that the iRNA of the repressor was heterogenous and its major peaks had the sedimentation constants of 10S, 22S and 32S. Poly(A)-containing RNA of the repressor was isolated from the summation compound. It had a high specific activity.
- Subjects :
- Animals
Cells, Cultured
Chick Embryo
Interferon Inducers pharmacology
Methods
Poly A isolation & purification
Protein Biosynthesis
RNA, Messenger analysis
Time Factors
Interferons antagonists & inhibitors
RNA, Messenger isolation & purification
Repressor Proteins analysis
Transcription Factors analysis
Subjects
Details
- Language :
- Russian
- ISSN :
- 0003-5637
- Volume :
- 25
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Antibiotiki
- Publication Type :
- Academic Journal
- Accession number :
- 7362228