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Studies on visceral Leishmania tropica infection in BALB/c mice. I. Clinical features and cellular changes.
- Source :
-
Clinical and experimental immunology [Clin Exp Immunol] 1981 Dec; Vol. 46 (3), pp. 493-8. - Publication Year :
- 1981
-
Abstract
- The visceral and lethal infection produced in BALB/c mice by Leishmania tropica (major) is accompanied by splenomegaly, anaemia and reversal of albumin-to-globulin ratio. The percentages of both B and T cells are decreased in the spleen. The spleen and lymph nodes become populated with large Ig-, Thy 1.2- 'null' cells. The similarity of some of these parameters with those produced in human kala-azar is discussed.
Details
- Language :
- English
- ISSN :
- 0009-9104
- Volume :
- 46
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Clinical and experimental immunology
- Publication Type :
- Academic Journal
- Accession number :
- 7337976