Formalin stress reaction of germfree and conventional mice treated with Bordetella pertussis vaccine.

Authors :: Anderlik P
Wessely M
Szeri I
Bános Z
Rápolthy IU
Budai J
Source :: Acta microbiologica Academiae Scientiarum Hungaricae [Acta Microbiol Acad Sci Hung] 1981; Vol. 28 (4), pp. 359-65.
Publication Year :: 1981
Abstract: Germfree and conventional mice responded similarly to pertussis vaccine treatment. In both groups, lymphocytosis and splenomegaly developed in a similar proportion. The formalin stress reaction of germfree and conventional mice with hypertrophic lymphoid organs induced by pertussis vaccine differed from that of untreated mice: the treated germfree and conventional mice showed a acute increase of lymphocytosis without an significant change in splenomegaly.

Subjects :: Animals
Female
Formaldehyde adverse effects
General Adaptation Syndrome chemically induced
Germ-Free Life
In Vitro Techniques
Leukocyte Count
Lymphocytes cytology
Lymphocytes drug effects
Male
Mice
Mice, Inbred Strains
Organ Size drug effects
Spleen drug effects
General Adaptation Syndrome physiopathology
Lymphatic System drug effects
Pertussis Vaccine pharmacology
Stress, Physiological physiopathology

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