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Vascular trauma induced by clamping- correlation between surface ultrastructure and fibrinolytic activity.
- Source :
-
Acta chirurgica Scandinavica [Acta Chir Scand] 1981; Vol. 147 (1), pp. 25-32. - Publication Year :
- 1981
-
Abstract
- The effects of application of a vascular clamp for 30 sec were studied on the femoral vessels in rats. Control and injured vessel segments were studied with scanning electron microscopy and with a histochemical method to estimate the fibrinolytic activity in the vessel walls. Endothelial injury with loss of endothelial cells was induced by application of the clamp. This was correlated to a reduction of the fibrinolytic activity in the vessel wall. In arteries re-endothelialization was seen three weeks after induction of the trauma, and it was completed after eight weeks. Venous lesions healed earlier. The re-endothelialization was followed by a return to normal fibrinolytic activity.
Details
- Language :
- English
- ISSN :
- 0001-5482
- Volume :
- 147
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Acta chirurgica Scandinavica
- Publication Type :
- Academic Journal
- Accession number :
- 7234273