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Thyroid hormone-catecholamine interrelationships during exposure to cold.
- Source :
-
Acta endocrinologica [Acta Endocrinol (Copenh)] 1981 May; Vol. 97 (1), pp. 91-7. - Publication Year :
- 1981
-
Abstract
- Basal plasma levels for adrenalin (A), noradrenalin (NA), L-triiodothyronine (T3), and L-thyroxine (T4) were determined in rats with a chronically inserted catheter. The experiments described in this report were started 3 days after the surgical procedure when T3 and T4 levels had returned to normal. Basal levels for the catecholamines were reached already 4 h after the operation. The T3/T4 ratio in plasma was significantly increased after 3, 7, and 14 days in rats kept at 4 degrees C and the same holds for the iodide in the 24-h urine after 7 and 14 days at 4 degrees C. The venous NA plasma concentration was increased 6- to 12-fold during the same period of exposure to cold, whereas the A concentration remained at the basal level. During infusion of NA at 23 degrees C the T3/T4 ratio in plasma was significantly increased after 7 days compared to pair-fed controls, and the same holds for the iodide excretion in the 24-h urine. This paper presents further evidence for a role of the sympathetic nervous system on T4 metabolism in rats at resting conditions.
Details
- Language :
- English
- ISSN :
- 0001-5598
- Volume :
- 97
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Acta endocrinologica
- Publication Type :
- Academic Journal
- Accession number :
- 7223318
- Full Text :
- https://doi.org/10.1530/acta.0.0970091