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Norepinephrine and gamma-aminobutyric acid in amyotrophic lateral sclerosis.
- Source :
-
Neurology [Neurology] 1980 Jan; Vol. 30 (1), pp. 98-101. - Publication Year :
- 1980
-
Abstract
- Patients with amyotrophic lateral sclerosis have increased levels of the neutrotransmitter norepinephrine in blood and cerebrospinal fluid and depressed levels of the inhibitory neurotransmitter gamma-aminobutyric acid in cerebrospinal fluid. These neurochemical alterations are most marked in patients bedridden with advanced disease, appear interrelated, and lead to cardiovascular alterations in patients with amyotrophic lateral sclerosis.
- Subjects :
- Adult
Amyotrophic Lateral Sclerosis blood
Female
Humans
Male
Muscular Diseases blood
Muscular Diseases cerebrospinal fluid
Nervous System Diseases blood
Nervous System Diseases cerebrospinal fluid
Norepinephrine blood
gamma-Aminobutyric Acid blood
Amyotrophic Lateral Sclerosis cerebrospinal fluid
Norepinephrine cerebrospinal fluid
gamma-Aminobutyric Acid cerebrospinal fluid
Subjects
Details
- Language :
- English
- ISSN :
- 0028-3878
- Volume :
- 30
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Neurology
- Publication Type :
- Academic Journal
- Accession number :
- 7188643
- Full Text :
- https://doi.org/10.1212/wnl.30.1.98