Back to Search
Start Over
Acquired Gaucher's cells in Hodgkin's disease.
- Source :
-
The American journal of medicine [Am J Med] 1982 Aug; Vol. 73 (2), pp. 290-4. - Publication Year :
- 1982
-
Abstract
- A patient with Hodgkin's disease associated with low glucocerebrosidase levels in the peripheral leukocytes, and Gaucher's cells in the bone marrow and lymph nodes, is described. After MOPP therapy, complete remission of Hodgkin's disease was accompanied by normalization of the glucocerebrosidase level and disappearance of Gaucher's cells. This observation appears unique when compared with the four cases of combined Hodgkin's and Gaucher's disease reported in earlier literature in which Gaucher's disease remained unchanged after chemotherapy. We conclude that our patient had Hodgkin's disease and acquired Gaucher's cells with diminished glucocerebrosidase levels, rather than a combination of Hodgkin's disease and Gaucher's disease.
- Subjects :
- Adult
Aged
Female
Gaucher Disease complications
Hodgkin Disease complications
Hodgkin Disease enzymology
Humans
Leukocytes enzymology
Male
Middle Aged
Bone Marrow pathology
Gaucher Disease pathology
Glucosidases metabolism
Glucosylceramidase metabolism
Hodgkin Disease pathology
Lymph Nodes pathology
Subjects
Details
- Language :
- English
- ISSN :
- 0002-9343
- Volume :
- 73
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The American journal of medicine
- Publication Type :
- Academic Journal
- Accession number :
- 7114083
- Full Text :
- https://doi.org/10.1016/0002-9343(82)90191-7