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Chemical modification of neamine.

Authors :
Suami T
Nishyama S
Ishikawa Y
Katsura S
Source :
Carbohydrate research [Carbohydr Res] 1978 Aug; Vol. 65 (1), pp. 57-64.
Publication Year :
1978

Abstract

The aminocyclitol antibiotic neamine has been modified by changing the configuration of one or two hydroxyl groups of the aminocyclitol moiety to elucidate the relationship between configuration and antimicrobial activity. 5-Epi-, 6-epi-, and 5,6-diepineamine have been prepared and their antimicrobial activity has been determined against several micro-organisms.

Details

Language :
English
ISSN :
0008-6215
Volume :
65
Issue :
1
Database :
MEDLINE
Journal :
Carbohydrate research
Publication Type :
Academic Journal
Accession number :
698978
Full Text :
https://doi.org/10.1016/s0008-6215(00)84212-3