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Acute lymphocytic leukemia with microblastosis and near haploidy (26 chromosomes): a case report.
- Source :
-
Medical and pediatric oncology [Med Pediatr Oncol] 1982; Vol. 10 (1), pp. 53-9. - Publication Year :
- 1982
-
Abstract
- A three-year-old acute lymphocytic leukemia (ALL) patient had a modal chromosome count of 26 in her bone marrow metaphases. The leukemia was "common" ALL by cytochemical and immunologic studies. Five other cases had been reported previously, and all have had a near haploidy varying from 26 to 32 chromosomes. Disomy of chromosomes 18 and 21 is a consistent feature of this disease. Severe hypodiploidy correlates with microblastosis requiring morphologic separation from non-neoplastic small lymphocytes.
- Subjects :
- Adolescent
Bone Marrow ultrastructure
Child
Child, Preschool
Chromosomes, Human, 16-18
Chromosomes, Human, 21-22 and Y
Diploidy
Female
Humans
Karyotyping
Leukemia, Lymphoid ultrastructure
Male
Metaphase
Middle Aged
Bone Marrow immunology
Haploidy
Leukemia, Lymphoid immunology
Lymphocytes ultrastructure
Subjects
Details
- Language :
- English
- ISSN :
- 0098-1532
- Volume :
- 10
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Medical and pediatric oncology
- Publication Type :
- Academic Journal
- Accession number :
- 6950203
- Full Text :
- https://doi.org/10.1002/mpo.2950100109