Biosynthesis of vitamin B12: identity of fragment extruded during ring contraction to the corrin macrocycle.

Authors :: Battersby AR
Bushell MJ
Jones C
Lewis NG
Pfenninger A
Source :: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1981 Jan; Vol. 78 (1), pp. 13-5.
Publication Year :: 1981
Abstract: Incorporation experiments with labeled sirohydrochlorin and trimethylisobacteriochlorin demonstrate that ring contraction in vivo to the corrin macrocycle of vitamin B12 liberates acetic acid. The C-20 atom of the precursors becomes the acetate carboxyl carbon.

Subjects :: Acetates biosynthesis
Bacteriochlorophylls metabolism
Cell-Free System
Chemical Phenomena
Chemistry
Corrinoids
Propionibacterium metabolism
Vitamin B 12 metabolism
Vitamin B 12 biosynthesis

Language :: English
ISSN :: 0027-8424
Volume :: 78
Issue :: 1
Database :: MEDLINE
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 6938990
Full Text :: https://doi.org/10.1073/pnas.78.1.13

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