Back to Search
Start Over
Plasma noradrenaline and adrenaline concentrations and dopamine-beta-hydroxylase activity in patients with shock due to septicaemia, trauma and haemorrhage.
- Source :
-
The Quarterly journal of medicine [Q J Med] 1978 Jan; Vol. 47 (185), pp. 1-20. - Publication Year :
- 1978
-
Abstract
- Plasma adrenaline and noradrenaline concentrations and dopamine-beta-hydroxylase activities were measured in patients with septicaemic, traumatic or haemorrhagic shock. Irrespective of the type of shock plasma adrenaline and noradrenaline concentrations were increased above the normal range. This is in keeping with the clinical features of increased sympathetic nervous system and adrenal medullary activity present in these patients. Plasma dopamine-beta-hydroxylase activities were within the normal limits in all forms of shock indicating the poor relationship of this measurement to sympathetic nervous system activity. In patients who died plasma noradrenaline concentrations remained persistently elevated above normal while in those who survived there was a rapid decline towards the normal range.
- Subjects :
- Adolescent
Adrenal Medulla physiopathology
Adult
Aged
Blood Pressure
Female
Heart Rate
Humans
Male
Middle Aged
Sepsis blood
Shock enzymology
Shock physiopathology
Shock, Hemorrhagic blood
Shock, Septic blood
Shock, Traumatic blood
Sympathetic Nervous System physiopathology
Dopamine beta-Hydroxylase metabolism
Epinephrine blood
Norepinephrine blood
Shock blood
Subjects
Details
- Language :
- English
- ISSN :
- 0033-5622
- Volume :
- 47
- Issue :
- 185
- Database :
- MEDLINE
- Journal :
- The Quarterly journal of medicine
- Publication Type :
- Academic Journal
- Accession number :
- 674546