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The effect of aluminum on the metabolism of embryonic chick bone in tissue culture.

Authors :
Miyahara T
Hayashi M
Kozuka H
Source :
Toxicology letters [Toxicol Lett] 1984 May; Vol. 21 (2), pp. 237-40.
Publication Year :
1984

Abstract

The effect of aluminum (Al) on bone metabolism was assessed in organ cultures of embryonic chick bone. Al of 10(-4)M and above caused an inhibitory effect on mineralization without inhibiting matrix formation and a stimulative effect on demineralization without stimulating matrix degradation. Therefore, Al was shown to influence the mineral metabolism of bone.

Subjects

Subjects :
Animals
Bone Resorption drug effects
Bone and Bones drug effects
Calcium metabolism
Chick Embryo
Minerals metabolism
Aluminum pharmacology
Bone and Bones metabolism

Details

Language :
English
ISSN :
0378-4274
Volume :
21
Issue :
2
Database :
MEDLINE
Journal :
Toxicology letters
Publication Type :
Academic Journal
Accession number :
6719509
Full Text :
https://doi.org/10.1016/0378-4274(84)90213-3
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